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Structure: Internal structure identifier : 526982

An unprecedented access to trifluoromethylthiosugar derivatives from thiocyanate precursors upon treatment with trifluoromethyltrimethylsilane

Marie-Noëlle Bouchu , Sylvie Large , Michaela Steng , Bernard R. Langlois , Jean-Pierre Praly et al.
Carbohydrate Research, 1998, 314 (1-2), pp.37 - 45. ⟨10.1016/S0008-6215(98)00289-4⟩
Journal articles istex hal-01800131v1

Unsymmetrical α,ω-end-functionalized oligo(cyclohexylidenes): efficient synthesis and conformational analysis

Wael Zeinyeh , Sylvie Radix , Raphael Terreux , Julie-Anne Chemelle , Nadia Walchshofer et al.
Tetrahedron, 2016, 72 (27-28), pp.4032 - 4038. ⟨10.1016/j.tet.2016.05.040⟩
Journal articles hal-01800196v1

Preparation of trifluoromethyl sulfides or selenides from trifluoromethyl trimethylsilane and thiocyanates or selenocyanates

Thierry Billard , Sylvie Large , Bernard R. Langlois
Tetrahedron Letters, 1997, 38 (1), pp.65 - 68. ⟨10.1016/S0040-4039(96)02216-2⟩
Journal articles istex hal-01800102v1

Regioselective N-alkylation of imidazo[4,5-b]pyridine-4-oxide derivatives: an experimental and DFT study

Wael Zeinyeh , Julien Pilmé , Sylvie Radix , Nadia Walchshofer
Tetrahedron Letters, 2009, 50 (16), pp.1828 - 1833. ⟨10.1016/j.tetlet.2009.02.006⟩
Journal articles hal-01800189v1
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Unexpected Binding Mode of a Potent Indeno[1,2-b]indole-Type Inhibitor of Protein Kinase CK2 Revealed by Complex Structures with the Catalytic Subunit CK2α and Its Paralog CK2α′

Jennifer Hochscherf , Dirk Lindenblatt , Benedict Witulski , Robin Birus , Dagmar Aichele et al.
Pharmaceuticals, 2017, 10 ((4)98), ⟨10.3390/ph10040098⟩
Journal articles hal-01683237v1

Uncompetitive nanomolar dimeric indenoindole inhibitors of the human breast cancer resistance pump ABCG2

Nathalie Guragossian , Billel Belhani , Alexis Moreno , Magda Teixeira Nunes , Lucia Gonzalez-Lobato et al.
European Journal of Medicinal Chemistry, 2021, 211, pp.113017. ⟨10.1016/j.ejmech.2020.113017⟩
Journal articles hal-03032952v1

Biological exploration of a novel 1,2,4-triazole-indole hybrid molecule as antifungal agent

Fabrice Pagniez , Nicolas Lebouvier , Young Min Na , Isabelle Ourliac-Garnier , Carine Picot et al.
Journal of Enzyme Inhibition and Medicinal Chemistry, 2020, 35 (1), pp.398-403. ⟨10.1080/14756366.2019.1705292⟩
Journal articles hal-02455791v1

Development of Pharmacophore Model for Indeno[1,2-b]indoles as Human Protein Kinase CK2 Inhibitors and Database Mining

Samer Haidar , Zouhair Bouaziz , Christelle Marminon , Tiomo Laitinen , Anti Poso et al.
3rd International Electronic Conference on Medicinal Chemistry, Nov 2017, Basel, Switzerland
Conference papers hal-02480388v1

Screening of indeno[1,2-b]indoloquinones by MALDI-MS: a new set of potential CDC25 phosphatase inhibitors brought to light

Faten Alchab , Estelle Sibille , Laurent Ettouati , Emilie Bana , Zouhair Bouaziz et al.
Journal of Enzyme Inhibition and Medicinal Chemistry, 2016, 31 (sup3), pp.25-32. ⟨10.1080/14756366.2016.1201480⟩
Journal articles hal-01655213v1

Synthesis and biological evaluation of zinc chelating compounds as metallo-β-lactamase inhibitors

Geir Kildahl-Andersen , Christian Schnaars , Anthony Prandina , Sylvie Radix , Marc Le Borgne et al.
MedChemComm, In press, 10 (4), pp.528-537. ⟨10.1039/C8MD00578H⟩
Journal articles hal-02077900v1

Comparison of SEC and AF4 analytical tools for size estimation of typhoid Vi polysaccharides

Caroline Bayart , Elisa Jean , Marie Paillagot , Alexia Renoud , Alice Raillard et al.
Analytical Methods, 2019, ⟨10.1039/C9AY00145J⟩
Journal articles hal-02288665v1

Progesterone–adenine hybrids as bivalent inhibitors of P-glycoprotein-mediated multidrug efflux: Design, synthesis, characterization and biological evaluation

Wael Zeinyeh , Zahia Mahiout , Sylvie Radix , Thierry Lomberget , Axel Dumoulin et al.
Steroids, 2012, 77 (12), pp.1177 - 1191. ⟨10.1016/j.steroids.2012.07.010⟩
Journal articles hal-01800194v1

Electrophilic Trifluoromethylation of Vinyl Sulfides

Bernard R. Langlois , Thierry Billard , Sophie Guérin , Sylvie Large , Nathalie Roidot-Perol et al.
Phosphorus, Sulfur, and Silicon and the Related Elements, 1999, 153 (1), pp.323 - 324. ⟨10.1080/10426509908546452⟩
Journal articles hal-01800163v1

Rearrangement of Oxasphiroheptanes to Cyclohexanones Mediated by Lithium Iodide

Bouyssi Didier , Marcello Cavicchioli , Sylvie Large , Monteiro Nuno , Geneviève Balme et al.
SYNLETT, 2000, 2000 (05), pp.0749 - 0751. ⟨10.1055/s-2000-6606⟩
Journal articles hal-01800154v1

A Regioselective Route to 5- and 6-Azaindoles

Thierry Lomberget , Sylvie Radix , Roland Barret
SYNLETT, 2005, 13, pp.2080 - 2082. ⟨10.1055/s-2005-871946⟩
Journal articles hal-01800182v1

Indeno[1,2-b]indole Inhibitors of Human Protein Kinase CK2 and Their Impact on Different Tumor Cell Lines (A021)

Dagmar Aichele , Marc Le Borgne , Joachim Jose
Second International Electronic Conference on Medicinal Chemistry (ECMC-2), Nov 2016, Bâle, Switzerland. pp.15/A021, ⟨10.3390/ph10010020⟩
Conference papers hal-01683452v1
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Functional display of heterotetrameric human protein kinase CK2 on Escherichia coli: a novel tool for drug discovery

Andre Gratz , Andre Bollacke , Sara Stephan , Christian Nienberg , Marc Le Borgne et al.
Microbial Cell Factories, 2015, 14 (74), ⟨10.1186/s12934-015-0263-z⟩
Journal articles hal-01683300v1

Synthesis and preclinical evaluation of TPA-based zinc chelators as metallo-β-lactamase inhibitors

Christian Schnaars , Geir Kildahl-Andersen , Anthony Prandina , Roya Popal , Sylvie Large Radix et al.
ACS Infectious Diseases, 2018, ⟨10.1021/acsinfecdis.8b00137⟩
Journal articles hal-01844562v1

Investigation of pharmacokinetic properties of CK2 Inhibitors with an Indeno[1,2-b]indole scaffold

Robin Birus , Marc Le Borgne , Joachim Jose
5th International Electronic Conference on Medicinal Chemistry, Nov 2019, Basel, Switzerland
Conference papers hal-02480385v1
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Carbazole scaffolds in cancer therapy: a review from 2012 to 2018

Samar Issa , Anthony Prandina , Nicolas Bedel , Pal Rongved , Saïd Yous et al.
Journal of Enzyme Inhibition and Medicinal Chemistry, 2019, 34 (1), pp.1321-1346. ⟨10.1080/14756366.2019.1640692⟩
Journal articles hal-02190476v1
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Diacritic Binding of an Indenoindole Inhibitor by CK2α Paralogs Explored by a Reliable Path to Atomic Resolution CK2α′ Structures

Dirk Lindenblatt , Anna Nickelsen , Violetta M Applegate , Jennifer Hochscherf , Benedict Witulski et al.
ACS Omega, 2019, 4 (3), pp.5471-5478. ⟨10.1021/acsomega.8b03415⟩
Journal articles hal-02077897v1
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In vitro effects of isoprinosine and of a dipeptide methyl ester on Echinococcus multilocularis.

Philippe Lawton , Nadia Walchshofer , Marie-Elisabeth Sarciron
Journal of Helminthology, 2001, 75 (3), pp.251-257. ⟨10.1079/JOH200049⟩
Journal articles istex hal-02110986v1

Mechanisms of drug-drug interaction between rifampicin and fusidic acid

Florianne Bel , Laurent Bourguignon , Michel Tod , Tristan Ferry , Sylvain Goutelle et al.
British Journal of Clinical Pharmacology, 2017, 83 (8), pp.1862-1864. ⟨10.1111/bcp.13277⟩
Journal articles hal-01911527v1
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Improved Surface Display of Human Hyal1 and Identification of Testosterone Propionate and Chicoric Acid as New Inhibitors

Isabelle Lengers , Fabian Herrmann , Marc Le Borgne , Joachim Jose
Pharmaceuticals, 2020, 13 (4), pp.54. ⟨10.3390/ph13040054⟩
Journal articles hal-02539544v1

81: Targeting casein kinase 2 in drug discovery: identification of new chemical entities

Zouhair Bouaziz , Samar Issa , Marc Le Borgne , Joachim Jose , Andreas Gratz et al.
Bulletin du Cancer, 97 (1(Supplement)), pp.S68-S69, 2010, Échappement Tumoral, ⟨10.1684/bdc.2010.1058⟩
Special issue hal-01691315v1
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1D NMR WaterLOGSY as an efficient method for fragment-based lead discovery

Claire Raingeval , Olivier Cala , Béatrice Brion , Marc Le Borgne , Roderick Eliot Hubbard et al.
Journal of Enzyme Inhibition and Medicinal Chemistry, 2019, 34 (1), pp.1218-1225. ⟨10.1080/14756366.2019.1636235⟩
Journal articles hal-02188259v1

Sequential MCR/Fisher indolization strategy for the construction of polycyclic carbazole derivatives

Esma Lamera , Sofiane Bouacida , Marc Le Borgne , Zouhair Bouaziz , Abdelmalek Bouraiou et al.
Tetrahedron Letters, 2017, 58 (13), pp.1305 - 1307. ⟨10.1016/j.tetlet.2017.02.047⟩
Journal articles hal-01683348v1

Design, Synthesis, X-ray Structure and Evaluation of Functionalized Hexacyclic Carbazoles as New Inhibitors of ABCG2 Transporter

Isadora da Silva Zanzarini , Esma Lamera , Sofiane Bouacida , Ingrid Fatima Zattoni , Diogo Henrique Kita et al.
5th International Electronic Conference on Medicinal Chemistry, Nov 2019, Basel, Switzerland
Conference papers hal-02480387v1
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QSAR Model of Indeno[1,2-b]indole Derivatives and Identification of N-isopentyl-2-methyl-4,9-dioxo-4,9-Dihydronaphtho[2,3-b]furan-3-carboxamide as a Potent CK2 Inhibitor

Samer Haidar , Christelle Marminon , Dagmar Aichele , Abdelhamid Nacereddine , Wael Zeinyeh et al.
Molecules, 2020, 25 (1), pp.97. ⟨10.3390/molecules25010097⟩
Journal articles hal-02424862v1

Improved biological performance of ketoprofen using novel modified halloysite clay nanotubes

Dounia Sid , Milad Baitiche , Lekhmici Arrar , Ferhat Djerboua , Riadh Bourzami et al.
Applied Clay Science, 2022, 216, pp.106341. ⟨10.1016/j.clay.2021.106341⟩
Journal articles hal-03475833v1