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Article Dans Une Revue Journal of Neuroscience Methods Année : 2022

Visualizing the cerebral distribution of chemical elements: a challenge met with LIBS elemental imaging

Résumé

Biological tissues contain various metals and metalloids ions with central role in the regulation of several pathophysiological functions. In parallel, the development and the evaluation of novel nanocompounds for biomedicine require the monitoring of their biodistribution in tissues of interest. Therefore, researchers need to use reliable and accessible techniques to detect and quantify major and trace elements in space-resolved manner. In this communication, we report how Laser-Induced Breakdown Spectroscopy (LIBS) can be used to image the distribution of chemical elements in brain tissues.
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Dates et versions

hal-03726566 , version 1 (18-07-2022)

Identifiants

Citer

Benoit Busser, Anne-Laure Bulin, Vincent Gardette, Hélène Elleaume, Frédéric Pelascini, et al.. Visualizing the cerebral distribution of chemical elements: a challenge met with LIBS elemental imaging. Journal of Neuroscience Methods, 2022, pp.109676. ⟨10.1016/j.jneumeth.2022.109676⟩. ⟨hal-03726566⟩
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