Impact of the Autophagy Machinery on Hepatitis C Virus Infection - Université Claude Bernard Lyon 1 Accéder directement au contenu
Article Dans Une Revue Viruses Année : 2011

Impact of the Autophagy Machinery on Hepatitis C Virus Infection

Résumé

Autophagy is a cellular process that catabolizes cytoplasmic components and maintains energy homeostasis. As a stress response, the autophagy machinery interconnects a wide range of cellular pathways, enhancing the spread of certain pathogens while limiting others, and has become a highly active research area over the past several years. Independent laboratories have recently reported that autophagy vesicles accumulate in hepatitis C virus (HCV) infected cells and that autophagy proteins can function as proviral factors required for HCV replication. In this review, we summarize what is currently known about the interplay between autophagy and HCV and the possible mechanisms whereby autophagy proteins might favor HCV propagation.
Fichier principal
Vignette du fichier
viruses-03-01342.pdf (146.79 Ko) Télécharger le fichier
Origine : Fichiers éditeurs autorisés sur une archive ouverte

Dates et versions

hal-03294528 , version 1 (21-07-2021)

Identifiants

Citer

Marlène Dreux, Francis V Chisari. Impact of the Autophagy Machinery on Hepatitis C Virus Infection. Viruses, 2011, 3 (8), pp.1342-1357. ⟨10.3390/v3081342⟩. ⟨hal-03294528⟩
40 Consultations
25 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More