Cross sectional study on prevalence of sickle cell alleles S and C among patients with mild malaria in Ivory Coast - Archive ouverte HAL Access content directly
Journal Articles BMC Research Notes Year : 2018

Cross sectional study on prevalence of sickle cell alleles S and C among patients with mild malaria in Ivory Coast

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Abstract

Sickle cell anemia is due to a mutations on the betaglobin gene, inducing abnormal hemoglobin. In West Africa the main mutations lead to S or C types of hemoglobin. Patients with homozygote mutations seem protected against severe malaria, but not against mild disease. The prevalence of abnormal hemoglobin among patients attending dispensaries for mild malaria is thus unknown. A retrospective study was conducted to update data on the prevalence of S and C hemoglobin among patients attending dispensaries with mild malaria. Enrolment of patients was conducted during in vivo malaria treatment efficacy survey following the 42 days WHO protocol. A group of non-infected pregnant women and a group of patients with fever different from malaria, were also recruited in the same dispensaries.

Dates and versions

hal-02329338 , version 1 (23-10-2019)

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Stephane Koui Tossea, Eric Gbessi Adji, Baba Coulibaly, Berenger Ako Ako, David Ngolo Coulibaly, et al.. Cross sectional study on prevalence of sickle cell alleles S and C among patients with mild malaria in Ivory Coast. BMC Research Notes, 2018, 11 (1), ⟨10.1186/s13104-018-3296-7⟩. ⟨hal-02329338⟩
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