Drosophila Protamine-Like Mst35Ba and Mst35Bb Are Required for Proper Sperm Nuclear Morphology But Are Dispensable for Male Fertility - Université Claude Bernard Lyon 1 Accéder directement au contenu
Article Dans Une Revue G3 Année : 2014

Drosophila Protamine-Like Mst35Ba and Mst35Bb Are Required for Proper Sperm Nuclear Morphology But Are Dispensable for Male Fertility

S. Kimura
  • Fonction : Auteur
L. Sapey-Triomphe
  • Fonction : Auteur
W. Sullivan
  • Fonction : Auteur
F. Landmann
  • Fonction : Auteur
B. Loppin
  • Fonction : Auteur

Résumé

During spermiogenesis, histones are massively replaced with protamines. A previous report showed that Drosophila males homozygous for a genomic deletion covering several genes including the protamine-like genes Mst35Ba/b are surprisingly fertile. Here, we have precisely deleted the Mst35B locus by homologous recombination, and we confirm the dispensability of Mst35Ba/b for fertility.

Dates et versions

hal-02045528 , version 1 (22-02-2019)

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Samantha Tirmarche, S. Kimura, L. Sapey-Triomphe, W. Sullivan, F. Landmann, et al.. Drosophila Protamine-Like Mst35Ba and Mst35Bb Are Required for Proper Sperm Nuclear Morphology But Are Dispensable for Male Fertility. G3, 2014, 4 (11), pp.2241-2245. ⟨10.1534/g3.114.012724⟩. ⟨hal-02045528⟩
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