Anakinra delayed skin allergy expressing as both injection site reactions and generalized exanthema
Résumé
Anakinra is a human interleukin-1 receptor antagonist (r-metHul-1ra), produced by recombinant DNA technology using an E. coli bacterial expression system. It is indicated for the treatment of adult rheumatoid arthritis (RA) in association with methotrexate [1]. Only a few cases of immediate allergic hypersensitivity to anakinra have been so far reported. We report a case of allergic delayed hypersensitivity to anakinra in a patient with RA.A 48-year-old male patient with RA had, over a period of [...]