<?xml version="1.0" encoding="utf-8"?>
<TEI xmlns="http://www.tei-c.org/ns/1.0" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:hal="http://hal.archives-ouvertes.fr/" xmlns:gml="http://www.opengis.net/gml/3.3/" xmlns:gmlce="http://www.opengis.net/gml/3.3/ce" version="1.1" xsi:schemaLocation="http://www.tei-c.org/ns/1.0 http://api.archives-ouvertes.fr/documents/aofr-sword.xsd">
  <teiHeader>
    <fileDesc>
      <titleStmt>
        <title>HAL TEI export of hal-01838976</title>
      </titleStmt>
      <publicationStmt>
        <distributor>CCSD</distributor>
        <availability status="restricted">
          <licence target="https://creativecommons.org/publicdomain/zero/1.0/">CC0 1.0 - Universal</licence>
        </availability>
        <date when="2026-05-03T03:07:13+02:00"/>
      </publicationStmt>
      <sourceDesc>
        <p part="N">HAL API Platform</p>
      </sourceDesc>
    </fileDesc>
  </teiHeader>
  <text>
    <body>
      <listBibl>
        <biblFull>
          <titleStmt>
            <title xml:lang="en">Deliberate interruptions and changes of dose of inhaled corticosteroids by asthma patients: "a community pharmacy study"</title>
            <author role="aut">
              <persName>
                <forename type="first">L.</forename>
                <surname>Laforest</surname>
              </persName>
              <email type="md5">74b9efac4237c413190ec3e68da9e653</email>
              <email type="domain">univ-lyon1.fr</email>
              <idno type="idhal" notation="string">laurent-laforest</idno>
              <idno type="idhal" notation="numeric">20412</idno>
              <idno type="halauthorid" notation="string">2284-20412</idno>
              <idno type="IDREF">https://www.idref.fr/095161066</idno>
              <affiliation ref="#struct-421734"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">É</forename>
                <surname>van Ganse</surname>
              </persName>
              <idno type="halauthorid">1398280-0</idno>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">G.</forename>
                <surname>Devouassoux</surname>
              </persName>
              <idno type="halauthorid">788464-0</idno>
              <affiliation ref="#struct-205255"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">G.</forename>
                <surname>Chatté</surname>
              </persName>
              <idno type="halauthorid">1087143-0</idno>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">C.</forename>
                <surname>Tamberou</surname>
              </persName>
              <idno type="halauthorid">1398281-0</idno>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">M.</forename>
                <surname>Belhassen</surname>
              </persName>
              <idno type="halauthorid">1355929-0</idno>
              <affiliation ref="#struct-421734"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">G.</forename>
                <surname>Chamba</surname>
              </persName>
              <idno type="halauthorid">1398282-0</idno>
            </author>
            <editor role="depositor">
              <persName>
                <forename>Christelle</forename>
                <surname>Cheval</surname>
              </persName>
              <email type="md5">7a04b984c0913330e8e8f067bb704ed2</email>
              <email type="domain">univ-lyon1.fr</email>
            </editor>
          </titleStmt>
          <editionStmt>
            <edition n="v1" type="current">
              <date type="whenSubmitted">2018-07-13 16:45:27</date>
              <date type="whenModified">2025-07-25 03:29:49</date>
              <date type="whenReleased">2018-07-13 16:45:27</date>
              <date type="whenProduced">2015-01</date>
            </edition>
            <respStmt>
              <resp>contributor</resp>
              <name key="318410">
                <persName>
                  <forename>Christelle</forename>
                  <surname>Cheval</surname>
                </persName>
                <email type="md5">7a04b984c0913330e8e8f067bb704ed2</email>
                <email type="domain">univ-lyon1.fr</email>
              </name>
            </respStmt>
          </editionStmt>
          <publicationStmt>
            <distributor>CCSD</distributor>
            <idno type="halId">hal-01838976</idno>
            <idno type="halUri">https://univ-lyon1.hal.science/hal-01838976</idno>
            <idno type="halBibtex">laforest:hal-01838976</idno>
            <idno type="halRefHtml">&lt;i&gt;Revue des Maladies Respiratoires&lt;/i&gt;, 2015, 32 (1), pp.8--17. &lt;a target="_blank" href="https://dx.doi.org/10.1016/j.rmr.2014.04.103"&gt;&amp;#x27E8;10.1016/j.rmr.2014.04.103&amp;#x27E9;&lt;/a&gt;</idno>
            <idno type="halRef">Revue des Maladies Respiratoires, 2015, 32 (1), pp.8--17. &amp;#x27E8;10.1016/j.rmr.2014.04.103&amp;#x27E9;</idno>
            <availability status="restricted"/>
          </publicationStmt>
          <seriesStmt>
            <idno type="stamp" n="HCL">Hospices Civils de Lyon</idno>
            <idno type="stamp" n="UNIV-LYON1">Université Claude Bernard - Lyon I</idno>
            <idno type="stamp" n="SANTE_PUB_INSERM" corresp="INSERM">Santé Publique à l'Inserm</idno>
            <idno type="stamp" n="CHLS" corresp="HCL">Centre Hospitalier Lyon Sud</idno>
            <idno type="stamp" n="UDL">UDL</idno>
            <idno type="stamp" n="UNIV-LYON">Université de Lyon</idno>
            <idno type="stamp" n="RESHAPE" corresp="UNIV-LYON1">Unité U1290 RESHAPE (RESearch on HealthcAre PErformance)</idno>
          </seriesStmt>
          <notesStmt>
            <note type="audience" n="2">International</note>
            <note type="popular" n="0">No</note>
            <note type="peer" n="1">Yes</note>
          </notesStmt>
          <sourceDesc>
            <biblStruct>
              <analytic>
                <title xml:lang="en">Deliberate interruptions and changes of dose of inhaled corticosteroids by asthma patients: "a community pharmacy study"</title>
                <author role="aut">
                  <persName>
                    <forename type="first">L.</forename>
                    <surname>Laforest</surname>
                  </persName>
                  <email type="md5">74b9efac4237c413190ec3e68da9e653</email>
                  <email type="domain">univ-lyon1.fr</email>
                  <idno type="idhal" notation="string">laurent-laforest</idno>
                  <idno type="idhal" notation="numeric">20412</idno>
                  <idno type="halauthorid" notation="string">2284-20412</idno>
                  <idno type="IDREF">https://www.idref.fr/095161066</idno>
                  <affiliation ref="#struct-421734"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">É</forename>
                    <surname>van Ganse</surname>
                  </persName>
                  <idno type="halauthorid">1398280-0</idno>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">G.</forename>
                    <surname>Devouassoux</surname>
                  </persName>
                  <idno type="halauthorid">788464-0</idno>
                  <affiliation ref="#struct-205255"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">G.</forename>
                    <surname>Chatté</surname>
                  </persName>
                  <idno type="halauthorid">1087143-0</idno>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">C.</forename>
                    <surname>Tamberou</surname>
                  </persName>
                  <idno type="halauthorid">1398281-0</idno>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">M.</forename>
                    <surname>Belhassen</surname>
                  </persName>
                  <idno type="halauthorid">1355929-0</idno>
                  <affiliation ref="#struct-421734"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">G.</forename>
                    <surname>Chamba</surname>
                  </persName>
                  <idno type="halauthorid">1398282-0</idno>
                </author>
              </analytic>
              <monogr>
                <idno type="halJournalId" status="VALID">21348</idno>
                <idno type="issn">0761-8425</idno>
                <idno type="eissn">1776-2588</idno>
                <title level="j">Revue des Maladies Respiratoires</title>
                <imprint>
                  <publisher>Elsevier Masson</publisher>
                  <biblScope unit="volume">32</biblScope>
                  <biblScope unit="issue">1</biblScope>
                  <biblScope unit="pp">8--17</biblScope>
                  <date type="datePub">2015-01</date>
                </imprint>
              </monogr>
              <idno type="doi">10.1016/j.rmr.2014.04.103</idno>
              <idno type="pubmed">25618199</idno>
            </biblStruct>
          </sourceDesc>
          <profileDesc>
            <langUsage>
              <language ident="en">English</language>
            </langUsage>
            <textClass>
              <keywords scheme="author">
                <term xml:lang="en"> Pharmacie</term>
                <term xml:lang="en">Female</term>
                <term xml:lang="en"> Humans</term>
                <term xml:lang="en"> Male</term>
                <term xml:lang="en"> Adolescent</term>
                <term xml:lang="en"> Adult</term>
                <term xml:lang="en"> Young Adult</term>
                <term xml:lang="en"> Patient Compliance</term>
                <term xml:lang="en"> Asthma</term>
                <term xml:lang="en"> Self Report</term>
                <term xml:lang="en"> Self Concept</term>
                <term xml:lang="en"> Drug Utilization</term>
                <term xml:lang="en"> Observance</term>
                <term xml:lang="en"> Corticoïdes inhalés</term>
                <term xml:lang="en"> Contrôle de l\textquoterightasthme</term>
                <term xml:lang="en"> Community pharmacies</term>
                <term xml:lang="en"> Asthma control</term>
                <term xml:lang="en"> Inhaled corticosteroids</term>
                <term xml:lang="en"> Adherence</term>
                <term xml:lang="en"> Pharmacies</term>
                <term xml:lang="en"> Patient Education as Topic</term>
                <term xml:lang="en"> Anti-Asthmatic Agents</term>
                <term xml:lang="en"> Asthme</term>
              </keywords>
              <classCode scheme="halDomain" n="sdv.spee">Life Sciences [q-bio]/Santé publique et épidémiologie</classCode>
              <classCode scheme="halTypology" n="ART">Journal articles</classCode>
              <classCode scheme="halOldTypology" n="ART">Journal articles</classCode>
              <classCode scheme="halTreeTypology" n="ART">Journal articles</classCode>
            </textClass>
            <abstract xml:lang="en">
              <p>BACKGROUND: Adherence to inhaled corticosteroids (ICS) remains a major issue for asthma management, even among patients receiving a regular prescription from their doctor. The frequency of deliberate interruption of ICS, and of spontaneous changes of dose, were studied in a population of asthma patients recruited in community pharmacies. METHODS: Asthma patients (aged 18-50) recruited in community pharmacies reported in self-administered questionnaires their spontaneous interruptions and changes of doses of ICS during the past 3 months. The characteristics of patients who interrupted their therapy or who modified the dose were compared with other patients. RESULTS: The studied population included 252 patients (mean age 35 year-old, females: 59%), of whom 62% had inadequately controlled asthma. Among these patients, 25% had interrupted ICS therapy during the past 3 months, while 21% spontaneously changed the dose. The most reported reason for interrupting ICS was the cessation of symptoms (50%). In multivariate analysis, interrupting ICS was mainly associated with inadequate asthma control (OR=3.1, 95% CI 1.5-6.4), while the strongest association with changing ICS doses was the patients' perception of asthma as a concern in their lives (OR=3.2, 95% CI 1.2-8.4). CONCLUSION: These results underline a poor understanding of the purpose of ICS therapy by patients. They also highlight the need of therapeutic education to improve the management of the disease.</p>
            </abstract>
          </profileDesc>
        </biblFull>
      </listBibl>
    </body>
    <back>
      <listOrg type="structures">
        <org type="laboratory" xml:id="struct-421734" status="OLD">
          <idno type="IdRef">203652991</idno>
          <idno type="RNSR">201622306F</idno>
          <orgName>Health Service and Performance Research</orgName>
          <orgName type="acronym">HESPER</orgName>
          <date type="start">2016-01-01</date>
          <date type="end">2020-12-31</date>
          <desc>
            <address>
              <addrLine>Site Lacassagne 162 Avenue Lacassagne69424 Lyon 3e</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.hesper.fr</ref>
          </desc>
          <listRelation>
            <relation name="EA7425" active="#struct-194495" type="direct"/>
            <relation active="#struct-301088" type="indirect"/>
          </listRelation>
        </org>
        <org type="laboratory" xml:id="struct-205255" status="VALID">
          <orgName>Service de pneumologie [Centre Hospitalier Lyon Sud - HCL]</orgName>
          <desc>
            <address>
              <addrLine>Chemin du Grand Revoyet 69495 Pierre-Bénite</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.chu-lyon.fr/web/1846</ref>
          </desc>
          <listRelation>
            <relation active="#struct-353860" type="direct"/>
            <relation active="#struct-300074" type="indirect"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-194495" status="VALID">
          <idno type="IdRef">026402823</idno>
          <idno type="ISNI">0000000121686185</idno>
          <idno type="ROR">https://ror.org/029brtt94</idno>
          <orgName>Université Claude Bernard Lyon 1</orgName>
          <orgName type="acronym">UCBL</orgName>
          <desc>
            <address>
              <addrLine>43, boulevard du 11 novembre 1918, 69622 Villeurbanne cedex</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.univ-lyon1.fr/</ref>
          </desc>
          <listRelation>
            <relation active="#struct-301088" type="direct"/>
          </listRelation>
        </org>
        <org type="regroupinstitution" xml:id="struct-301088" status="VALID">
          <idno type="ROR">https://ror.org/01rk35k63</idno>
          <orgName>Université de Lyon</orgName>
          <desc>
            <address>
              <addrLine>92 rue Pasteur - CS 30122, 69361 Lyon Cedex 07</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.universite-lyon.fr/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-353860" status="VALID">
          <idno type="ROR">https://ror.org/023xgd207</idno>
          <orgName>Centre Hospitalier Lyon Sud [CHU - HCL]</orgName>
          <orgName type="acronym">CHLS</orgName>
          <desc>
            <address>
              <addrLine>165 Chemin du Grand Revoyet69495 Pierre-Bénite</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.chu-lyon.fr/fr/centre-hospitalier-lyon-sud</ref>
          </desc>
          <listRelation>
            <relation active="#struct-300074" type="direct"/>
          </listRelation>
        </org>
        <org type="regroupinstitution" xml:id="struct-300074" status="VALID">
          <idno type="IdRef">026534657</idno>
          <idno type="ROR">https://ror.org/01502ca60</idno>
          <orgName>Hospices Civils de Lyon</orgName>
          <orgName type="acronym">HCL</orgName>
          <desc>
            <address>
              <addrLine>3 Quai des Célestins69002 Lyon</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.chu-lyon.fr/fr/hospices-civils-de-lyon-hcl</ref>
          </desc>
        </org>
      </listOrg>
    </back>
  </text>
</TEI>