EBV-associated nasopharyngeal carcinomas: from epidemiology to virus-targeting strategies. - Université Claude Bernard Lyon 1 Accéder directement au contenu
Pré-Publication, Document De Travail Année : 2006

EBV-associated nasopharyngeal carcinomas: from epidemiology to virus-targeting strategies.

Résumé

Nasopharyngeal carcinoma is a human malignancy consistently associated with the Epstein-Barr virus. Exposure to non-viral carcinogens and genetic predisposition are other crucial etiologic factors. Tumor development appears to require the expression of a small subset of transforming viral RNAs and proteins with concomitant silencing of most other viral genes. Impairment of the interactions of viral proteins with cellular partners or disruption of viral latency might prove to be useful for novel therapeutic strategies.
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Dates et versions

hal-00120139 , version 1 (13-12-2006)

Identifiants

  • HAL Id : hal-00120139 , version 1
  • PUBMED : 15276610

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Pierre Busson, C. Keryer, T. Ooka, M. Corbex. EBV-associated nasopharyngeal carcinomas: from epidemiology to virus-targeting strategies.. 2006. ⟨hal-00120139⟩
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